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KMID : 1140920170410030493
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Annals of Rehabilitation Medicine
2017 Volume.41 No. 3 p.493 ~ p.497
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Diagnosis of Churg-Strauss Syndrome Presented With Neuroendocrine Carcinoma: A Case Report
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Park Da-Yun
Lee Ho-Jun
Lee Kwang-Hoon
Kwon Bum-Sun
Park Jin-Woo
Nam Ki-Yeun
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Abstract
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Churg-Strauss syndrome (CSS) is a rare systemic vasculitis that affect small and medium-sized blood vessels and is accompanied by asthma, eosinophilia, and peripheral neuropathy. This report describes a case of a 52-year-old man who had a history of sinusitis, asthma, and thymus cancer and who had complained of bilateral lower extremity paresthesia and weakness for a month. Peripheral neuropathy was detected by electrodiagnostic studies. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit. After thymectomy, peripheral blood tests revealed a gradual increase in eosinophils. Two months after surgery, he was admitted to the hospital for dyspnea, and nodules of focal consolidation were found in his chest X-ray. One month later, pyoderma occurred in the right shin, and the skin biopsy showed extravascular eosinophilic infiltration. He was diagnosed with CSS after thymectomy, and we report a very rare case of CSS presented with thymic neuroendocrine carcinoma.
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KEYWORD
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Churg-Strauss syndrome, Thymic neuroendocrine carcinoma, Polyneuropathy
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